Glossary of terms

Glossary of terms
CSR report

Glossary of terms, to be read only in conjunction with this Q3 Report 2018.

1

100 points clinical response

Percentage of patients achieving a 100-point decrease in CDAI score during a clinical trial in CD patients
A

ACR

ACR20 (ACR 20/50/70)

Adenovirus

ADPKD

ADS

AFM

Anemia

Ankylosing spondylitis (AS)

Anti-TNF

Assays

ATS

Attrition rate

Autotaxin (ATX)

B

BID dosing

Bioavailability

Biomarker

Black & Scholes model

Bleomycin model

Bridging trial

C

CALOSOMA

Cash position

CDAI

CDAI remission

CFTR

CHIT1/AMCase

CHMP

CIR

Clinical Proof of Concept (PoC)

Complete Response Letter (CRL)

Compound

Contract research organization (CRO)

Corticosteroids

Crohn's disease (CD)

CRP

Cytokine

D

DARWIN

DDI study

Deep venous thrombosis (DVT)

Degradation

Development

Discovery

Disease-modifying

DIVERGENCE

DIVERSITY

DLCO

DMARDs

Dose-range finding study

Double-blind

E

Efficacy

EMA

Endoscopy

Esbriet

F

Fast Track

FDA

Fee-for-service

Fibrotic score

FIH

Filgotinib

FINCH

Fistulizing CD

FITZROY

FORM 20-F

FRI

FSMA

FTE

Futility analysis

FVC

G

G&A expenses

Genome

GLIDER

GLPG0555

GLPG0634

GLPG1205

GLPG1690

GLPG2737

GLPG3121

GLPG3667

GLPG3970

GLPG4059

GLPG4399

GLPG4586

GLPG4605

GLPG4716

GLPG4876

GPR84 inhibitor

H

HDL

Hemoglobin

Histology

Histopathology

I

IBD

In-/out-licensing

In vitro

In vivo

Inflammatory diseases

Inspiratory capacity

Intellectual property

Intersegment

Investigational New Drug (IND) Application

IPF

ISABELA

J

JAK

Jyseleca®

L

LADYBUG

LDL

Lipoprotein

Liver enzymes

Lymphocyte

M

MACE

MANTA

MANTA-RAy

MHLW

Milestone

Modulation

Molecule collections

MTX

N

NDA

Neutrophil

NICE

NK cells

O

Ofev

Oligonucleotide

Oral dosing

Osteoarthritis (OA)

Outsourcing

P

PCKD

Pharmacokinetics (PK)

Phase 1

Phase 2

Phase 3

Phenotypic screening

Pivotal trials

Placebo-controlled

Preclinical

Preclinical candidate (PCC)

Product candidate

Proof of Concept (POC)

Proof of Concept study

PROTAC

Psoriasis

Psoriatic arthritis (PsA)

Pulmonary embolism

Q

QD dosing

R

R&D operations

Replication

Rheumatoid arthritis (RA)

S

Screening

SEA TURTLE

SEC

SELECTION

SES-CD scores

Short interfering RNA

SIK

Sjögrens syndrome

S&M expenses

Small bowel CD (SBCD)

Statin

Systemic lupus erythematosus

T

TAPINOMA

Target

Target discovery

TEAE

Technology access fee

Toledo

Topical corticosteroids

Transcription

Translation

TYK

U

Ulcerative colitis (UC)

V

Venous thrombotic events

Z

Ziritaxestat