Consolidated statements of income and comprehensive income/loss (-)
| 
 | Year ended 31 December | 
 | |
|---|---|---|---|
| (thousands of €, except per share data) | 2022 | 2021 | Notes | 
| Product net sales | 87,599 | 14,753 | |
| Collaboration revenues | 417,681 | 470,093 | |
| Total net revenues | 505,280 | 484,846 | 
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| 
 | 
 | 
 | 
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| Cost of sales | (12,079) | (1,629) | 
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| Research and development expenditure | (515,083) | (491,707) | |
| Sales and marketing expenses | (147,555) | (69,956) | |
| General and administrative expenses | (144,931) | (140,899) | |
| Other operating income | 46,848 | 53,749 | |
| 
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 | 
 | 
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| Operating loss | (267,520) | (165,596) | 
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| 
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 | 
 | 
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| Fair value adjustments and net currency exchange differences | 51,473 | 61,296 | |
| Other financial income | 18,578 | 3,058 | |
| Other financial expenses | (17,679) | (21,757) | |
| 
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 | 
 | 
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| Loss before tax | (215,147) | (122,999) | 
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| 
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 | 
 | 
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| Income taxes | (2,844) | (2,423) | |
| 
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 | 
 | 
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| Net loss from continuing operations | (217,991) | (125,422) | 
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| 
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 | 
 | 
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| Net profit from discontinued operations, net of tax | - | 22,191 | |
| 
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| Net loss | (217,991) | (103,231) | 
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| 
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| Net loss attributable to: | 
 | 
 | 
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| Owners of the parent | (217,991) | (103,231) | 
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| Basic and diluted loss per share | (3.32) | (1.58) | |
| Basic and diluted loss per share from continuing operations | (3.32) | (1.91) | 
 | 
The accompanying notes form an integral part of these financial statements.
| 
 | Year ended 31 December | 
 | |
|---|---|---|---|
| (thousands of €) | 2022 | 2021 | Notes | 
| Net loss | (217,991) | (103,231) | 
 | 
| Items that will not be reclassified subsequently to profit or loss: | 
 | 
 | 
 | 
| Re-measurement of defined benefit obligation | 5,324 | 730 | 
 | 
| Items that may be reclassified subsequently to profit or loss: | 
 | 
 | 
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| Translation differences, arisen from translating foreign activities | 129 | 736 | 
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| 
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| Realization of translation differences upon sale of foreign operations | - | 731 | 
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| Other comprehensive income, net of  | 5,453 | 2,197 | 
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| 
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| Total comprehensive loss attributable to: | 
 | 
 | 
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| Owners of the parent | (212,538) | (101,034) | 
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| 
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 | 
 | 
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| Total comprehensive loss attributable to owners of the parent arises from: | 
 | 
 | 
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| Continuing operations | (212,538) | (123,956) | 
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| Discontinued operations | - | 22,922 | 
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| Total comprehensive loss | (212,538) | (101,034) | 
 | 
The accompanying notes form an integral part of these financial statements.